UHealth - University of Miami Health System

Xiang-Xi "Mike" Xu, Ph.D.

General Information



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  • English


  • Professor of Cell Biology

Clinical Interests

 Ovarian Cancer


Research Interests

Research page

Department of Cell Biology

Ovarian cancer Biology and early embryogenesis:

1.  Pre-malignant lesions in ovarian carcinogenesis

2.  Menopause and ovarian cancer risk

3.  Dab2 in endocytosis and signalings

4.  Primitive endoderm formation in early mouse embryogenesis

5.  Nuclear envelope changes and defects in stem cell differentiation and cancer


1989 Ph.D.
Emory University
1984 B.S.
Zhongshan University



 Xiang-Xi Mike Xu obtained his B.S. in Chemistry from ZhongShan University (China) in 1984, Ph.D. in Biochemistry from Emory University (Atlanta, GA) in 1989.  He did his postdoctoral training at Columbia University (New York, NY) (1989-1992); and St. Jude Children's Research Hospital (Memphis, TN) (1992-1995).  Dr. Xu started as an Assistant Professor at Department of Biochemistry and Winship Cancer Institute at Emory University (1996-2000), was an Associate Member at Fox Chase Cancer Center (Philadelphia, PA) (2000-2007), and started as a Professor at the University of Miami in 2008.

Dr. X. Mike Xu uses mouse modles to study ovarian cancer biology and etiology, and to investigate the formation of primitive endoderm in early blastocysts and embryos.