Francisca Diaz, PhD
General Information
Contact
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Languages
- English
Roles
- Research Assistant Professor
Clinical Interests
Neurology Basic Science
Education
1996 Postdoctoral Associate
University of Miami
1995 PhD
University of Toledo
1986 Licenciature
Universidad Simon Bolivar
Publications
- Diaz, F and Moraes CT. Mitochondrial biogenesis and turnover. 2008. Cell Calcium.44(1):24-35
- Wenz T, Diaz F, Spiegelman BM, Moraes CT. Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype. 2008. Cell Metab.8(3):249-56.
- Torraco A, Diaz F, Vempati UD, Moraes CT. Mouse models of oxidative phosphorylation defects: Powerful tools to study the pathobiology of mitochondrial diseases. 2008. Biochim Biophys Acta.Jun 13. [Epub ahead of print]
- Garcia S, Diaz F, Moraes CT. A 3' UTR modification of the mitochondrial rieske iron sulfur protein in mice produces a specific skin pigmentation phenotype. 2008.J Invest Dermatol.128(9):2343-5
- Diaz F, Garcia S, Hernandez D, Regev A, Rebelo A, Oca-Cossio J, Moraes CT. Pathophysiology and fate of hepatocytes in a mouse model of mitochondrial hepatopathies.2008. Gut.57(2):232-42
- Fukui H, Diaz F, Garcia S, Moraes CT. Cytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's disease.2007. Proc. Natl. Acad. Sci. U S A. 104(35):14163-8.
- Vempati UD, Diaz F, Barrientos A, Narisawa S, Mian AM, Miln JL, Boise LH, Moraes CT. Role of cytochrome C in apoptosis: increased sensitivity to tumor necrosis factor alpha is associated with respiratory defects but not with lack of cytochrome C release.2007. Mol Cell Biol. 27(5):1771-83.
- Diaz F, Fukui H, Garcia S, Moraes CT. Cytochrome c oxidase is required for the assembly/stability of respiratory complex I in mouse fibroblasts. 2006.Mol Cell Biol. 26(13):4872-81.
- Diaz F, Thomas CK, Garcia S, Hernandez D, Moraes CT. Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency. 2005. Hum Mol Genet. 14(18):2737-48.