Andrew V. Schally, Ph.D., MDhc (Multi), D.Sc
General Information
Contact
- Fax: 305-575-3126
- .(JavaScript must be enabled to view this email address)
Languages
- English
Roles
- Distinguished Leonard M. Miller Professor of Pathology & Professor of Hematology/Oncology, University of Miami Miller School of Medicine
- Distinguished Medical Research Scientist and Head of The Endocrine, Polypeptide and Cancer Institute, Veterans Affairs Medical Center
Clinical Interests
Clinical trials with peptide analogs of LH-RH, bombesin/GRP, somatostatin and GHRH on a variety of cancers including prostate and breast cancer. Treatment of BPH with Cetrorelix, targeted chemotherapy.
Research Interests
Development and evaluation of peptide analogs with antitumor activity including targeted cytotoxic analogs of LHRH, somatostatin and bombesin and antagonistic analogs of GHRH Inhibitory effects of peptide analogs on various cancers, including prostate cancer, pancreatic cancer, gastric cancer, colon cancer, malignant brain tumors, lung cancer (SCLC and non-SCLC), renal cancer and osteosarcomas, melanomas, hepatocellular carcinoma and lymphomas as well as breast cancers, ovarian cancers and endometrial cancers. Mechanism of action of GHRH antagonists and its receptors. Mechanism of action of LHRH antagonist Cetrorelix on BPH. Evaluation of hypothalamic peptide analogs in cardiology, diabetic nephropathy and Alzheimer's disease.