Mark Nash, Ph.D., FACSM
Among the organs most affected by spinal cord injury are those of the cardiovascular network. Cardiovascular disease after SCI occurs earlier in life and often without overt signs and symptoms of impending cardiac damage. In the process it compromises health, fitness, and function.
The focus of my work is to minimize medical complications associated with diseases of the cardiovascular system. This focus includes co-morbid disorders such as diabetes, dysmetabolic syndrome, and obesity. Research strategies involve testing of medicines to treat dyslipidemia accompanying spinal cord injury and reduce the burden of atherogenic lipid profiles on disease progression. These treatment strategies can be coupled with exercise conditioning, which can be provided under voluntary control or using electrically stimulated neuroprosthesis. The overarching goal of the work is to foster health and fitness so that optimal activity, life satisfaction, and productivity can be best maintained.