Cell signaling

Molecular basis of signal transduction: receptors, G proteins, kinases, cell Ca2+. Novel signaling pathways and protein complexes.

Neurons, pancreas, ocular tissues.

Microbiome, metagenomics, marine organisms.

 

• Differential effects of the Gß5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release
• Targeted deletion of one or two copies of the G protein ß subunit Gß5 gene has distinct effects on body weight and behavior in mice.
• Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions.
• Other publications by Dr. Slepak
• See Dr. Slepaks's PubMed Publications