Karl L. Magleby, Ph.D
General Information

Contact
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Languages
- English
Roles
- Professor and Chair of Physiology and Biophysics
Research Interests
Research interests are in three areas:
The mechanisms controlling the selectivity and conductance of ion channels.
The mechanisms controlling how ion channels gate their pores.
The mechanisms involved in short term synaptic plasticity.
Education
1971 Postdoctoral Fellowship
University of Washington
1970 PhD
University of Washington
1966 B.S.
University of Utah
Publications
- Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels. J. Gen Physiol. 2017, 149:373-387
- A genetic variant of the sperm-specific SLO3 K+ channel has altered pH and Ca2+ sensitivities. J Biol Chem. 2017 pii: jbc.M117.776013. doi: 10.1074/jbc.M117.776013
- Single-channel kinetics of BK (Slo1) channels. Front Physiol. 2015 Jan 21;5:532. doi: 10.3389/fphys.2014.00532. eCollection 2014.
- Exponential sum-fitting of dwell-time distributions without specifying starting parameters. Biophys J. 2013, 104:2383-91
- Properties of Slo1 K+ channels with and without the gating ring. Proc Natl Acad Sci U S A. 2013, 110:16657-62.
- COMPLETE BIBLIOGRAPHY
Biography
1971-1975 Assistant Professor, Department of Physiology and Biophysics, Univ. Miami Miller School Medicine
1975-1980 Associate Professor, Department of Physiology and Biophysics, Univ. Miami Miller School Medicine
1980- Professor, Department of Physiology and Biophysics, Univ. Miami Miller School of Medicine
1992- Chairman, Department of Physiology and Biophysics, Univ. Miami Miller School of Medicine