Physiological regulation of electrical activity (action- and resting potentials) and intracellular ion (Ca²⁺, Na⁺ and H⁺) homeostasis in axons and terminals of the peripheral nervous system, and how neurodegenerative diseases/conditions disrupt these processes.

• Nguyen, K.T., Zhang, Z., Barrett, E.F., David, G. (2012). Morphological and functional changes in innervation of a fast forelimb muscle in SOD1-G85R mice Neurobiology of Disease, 48 (3), pp. 399-408.
• Zhang, Z., Nguyen, K.T., Barrett, E.F., David, G. (2010). Vesicular ATPase Inserted into the Plasma Membrane of Motor Terminals by Exocytosis Alkalinizes Cytosolic pH and Facilitates Endocytosis. Neuron, 68 (6), pp. 1097-1108.
• Nguyen, K.T., García-Chacon, L.E., Barrett, J.N., Barrett, E.F., David, G.. (2009). The PSIm depolarization that accompanies mitochondrial Ca2+ uptake is greater in mutant SOD1 than in wild-type mouse motor terminals. Proceedings of the National Academy of Sciences of the United States of America, 106 (6), pp. 2007-2011.
• Link to publication list
• Zhang, Z., David, G. (2015). Stimulation-induced Ca2+ influx at nodes of Ranvier in mouse peripheral motor axons. The Journal of Physiology. 2015 Sep 14. doi: 10.1113/JP271207. [Epub ahead of print]