Photoreceptor cell biology, the mechanism of photoreceptor degeneration, Retinal and choroidal vascular disorders.

Research Summary

As a retinal cell biology lab, we focus on the changes in photoreceptor behaviors under different circumstances. Specifically, we are interested in the mechanism that regulates light-induced photoreceptor plasticity and the role of Müller cells in this regulatory mechanism. We are also trying to understand the mechanisms for photoreceptor degeneration, including hereditary retinal degeneration and age-related macular degeneration (AMD), and to search for potential treatments. In addition, we are developing experimental models to mimic human ocular vascular disorders including choroidal neovascularization (CNV) and diabetic retinopathy. The goal is to understand the biology of the retina and photoreceptors, the physiopathology of retinal diseases, and to translate the bench research to patient care.

Read more about Rong Wen's research projects

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