Vittorio D. Porciatti, D. Sc.
- English, Italian
- Director and Vice Chairman of Research, Bascom Palmer Eye Institute
- Professor of Ophthalmology, Neuroscience and Biomedical Engineering
Visual dysfunction in glaucoma and optic neuropathies, prevention and restoration
Death of retinal ganglion cells (RGCs) is the cause of blindness in glaucoma and of optic nerve diseases. The central idea of Dr. Porciatti’s research is that RGCs undergo a stage of reversible dysfunction before dying. If neuronal dysfunction is detected early, then visual loss can be timely prevented and neural function restored. Dr. Porciatti’s laboratory uses non-invasive electrophysiologic and imaging techniques in human and mouse models to investigate how RGCs become dysfunctional, how and when they become susceptible to stress, and how their function may be improved.