Sandra Merscher, Ph.D.
General Information

Contact
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Languages
- English
- English, German, French
Roles
- Director of Animal Core
- Research Associate Professor
CV
Research Interests
Using a basic science and translational research approach, my laboratory is focused on elucidating and understanding the molecular mechanisms that contribute to the development of proteinuria in kidney disease with a focus on focal segmental glomerulorsclerosis (FSGS) and diabetic kidney disease (DKD).
Kidney disease
Mouse models
Podocyte injury
Diabetic kidney disease
Focal segmental glomerulosclerosis
Cell signaling
Cholesterol
Lipids
Sphingolipids
TNF alpha
ABCA1
SMPDL3b.
Awards
Scientific Award Committee
Stanley J. Glaser Foundation Biomedical Research Award
Education
1999 Ph.D.
University of Saarland
Publications
Biography
Dr. Merscher obtained her Ph.D. degree in Human Genetics from the University of Saarland, Saarbrucken, Germany. For her postdoctoral fellowship, she joined Dr. Raju Kucherlapati’s Laboratory in the Department of Molecular Genetics at the Albert Einstein College of Medicine, Bronx, NY and at Brigham and Women’s Hospital, Harvard Medical School, Boston, MA where she worked on the generation and phenotypical analysis of mouse models for Velo-Cardio-Facial Syndrome. Since her postdoctoral fellowship, she has worked as Research Assistant Professor with several investigators from Mount Sinai School of Medicine, New York, NY and the University of Miami, Miller School of Medicine, Miami, FL. specializing in the generation of mouse models for proteinuric kidney diseases. Her research focuses on elucidating and understanding the molecular mechanisms that contribute to the development of proteinuria with a special emphasis on focal segmental glomerulorsclerosis (FSGS) and diabetic kidney disease (DKD).